Micotherapy Hericium

Support to the nervous system and gastrointestinal tract
Food supplement containing organically grown Hericium erinaceus (IT BIO 006) – Made in Europe.

Health benefits BIBLIOGRAPHY:
Also known as “Lion’s mane” or “Monkey’s mushroom”, Hericium is the mushroom of the digestive system and of the nervous system. Rich in vitamins and minerals, it was traditionally used for all gastric conditions, thanks to its anti-inflammatory, healing properties and ability to promote the regeneration of the gastrointestinal mucosa.

Properties:
Organically grown and titrated, today it is widely studied both for its benefits on the gastrointestinal system, with direct effects on the intestinal mucosa and immune regulation, and for its neurological support properties and therefore on the intestine-brain axis. Studies begun in 1991 have made it possible to identify in Hericium erinaceus low molecular weight compounds, erinacines and hericenones, capable of crossing the blood-brain barrier and stimulating myelin regeneration, thus promoting the maintenance of normal cognitive functions.

Ingredients:

  • Organically grown Hericium erinaceus, sporophorum dry extract titrated in Polysaccharides, Erinacin and Ergothioneine

Contained substances:

  • All essential amino acids
  • Polysaccharides and glycoproteins
  • Hericenones, Erinacin
  • Triterpenes, ergosterols, bioflavonoids
  • Alkaloids (Ericenine)
  • Fatty acids
  • Minerals: Potassium, Zinc, Iron, Germanium, Selenium, Phosphorus
  • Ergothioneine

Directions:
3 capsules per day, preferably away from meals.

Pack:
pack containing 90 capsules
vegetable cellulose capsules

Notes:
Gluten free
ICEA Organic certified product
No GMO
Made in Europe

AVERAGE CONTENT OF CHARACTERISING INGREDIENTS PER DAILY DOSE (3 CAPSULES)

Hericium sporophorum

 1200 mg

Hericium dry extract

 300 mg

Polysaccharides

 150 mg
Erinacine A

417 mcg

Ergothioneine

 346 mcg

BIBLIOGRAPHY:

  1. K Nagai, A Chiba, T Nishino, T Kubota, and H Kawagishi Dilinoleoyl-phosphatidylethanolamine from Hericium erinaceum protects against ER stress-dependent Neuro2a cell death via protein kinase C pathway. J Nutr Biochem, Aug 2006; 17(8): 525-30
  2. Kawagishi, H. et al. Hericenones C, D, and E, stimulators of Nerve Growth Factor synthesis, from the mushroom Hericium erinaceum. Tetrahedron Lett. 1991; 32, 4361-4564
  3. Kawagishi, H. et al. Chromans, Hericenones F, G, and H from the mushroom Hericium erinaceum. Phytochemistry. 1993; 32, 175-178
  4. Furukawa, S. et al. Biological Significance of Nerve Growth Factor and its Syntheses-Promoting Agent. Chemistry and Biology. 1991; 29. (In Japanese)
  5. Kawagishi, H. The Basic Chemistry of Mushrooms and Fungus and Biotechnology, Shishido, K. (editor). 2002; IPC, 212-228. (In Japanese)
  6. Kawagishi, H. Mushroom Yearbook 2002, Efficacy of Mushrooms and its Prospectives. Plants World. 2002; 227-332. (In Japanese)
  7. Kawagishi, H. Science of Mushrooms, Suguwara, R. (editor). Asakura Shoten. 1997; 155-180. (In Japanese)
  8. Kawagishi, H. et al. Search for Bioregulating Agents of Edible Mushrooms and Their Performance Analysis, Arai, S. (editor). Gakkai Shuppann Center, 1995; 37-43. (In Japanese)
  9. Kawagishi, H. et al. Nerve Growth Factor Synthesis-Promoting Agents, Approaches for Studying Vital Function Regulating Agents in Food. Gakkai Shuppan Center, 1996; 165-181. (In Japanese)
  10. Kawagishi, H. Bioregulating Agents Found in Mushrooms. Food and Development. 2002; 37: 14-17. (In Japanese)
  11. Kawagishi, H. Bioregulating Agents which Mushrooms Produce. ILSI. 2002; 70: 3-14. (In Japanese)
  12. Kawagishi, H. The Frontier of the Studies on Functionality of Mushrooms. Science of Food. 2002; 296: 4-12. (In Japanese)
  13. Kawagishi, H. Bioregulating Agents which Mushrooms Produce, Kinoko-ken Dayori. 2001; 18: 5-14. (In Japanese)
  14. Kawagishi, H. The Secondary Metabolites of Mushrooms that Promote Synthesis of Nerve Growth Factor. Japan Mycology Journal. 2001; 42: 11-16. (In Japanese)
  15. Kawagishi, H. Mushrooms are a Mine of Bioregulatory Agents with Unique Backbones and Functions. Chemistry and Biology. 2001; 39: 497-498. (In Japanese)
  16. Kawagishi, H. The Present Situation of Chemical Study on Functionality of Food. New Food Industry. 2001; 43: 25-35. (In Japanese)
  17. Kawagishi, H. “Good-For-Body” Agents that Edible Mushrooms Produce. Brain-Tech News. 2000; 81: 1-5. (In Japanese)
  18. Kawagishi, H. Mushroom-Derived Cellular Function Regulatory Agents. Agriculturization Magazine. 1994; 68: 671-677. (In Japanese)
  19. Kawagishi, H. et al. The Inducer of the Synthesis of Nerve Growth Factor from Lion’s Mane (Hericeum erinaceum). Explore! 2002; 11(4): 4-51
  20. Lee. E. W. et al. Two novel diterpenoids, erinacines H and I from the mycelia of Hericium erinaceum. Biosci. Biotechnol. Biochem. 2000; 64: 2402-2405
  21. Kawagishi, H. et al. Erinacine D, a stimulator of NGF-synthesis, from the mycelia of Hericium erinaceum. Heterocycl. Commun. 1996; 2: 51-54
  22. Kawagishi, H. et al. Erinacines, E, F, and G, stimulators of nerve growth factor synthesis, from the mycelia of Hericium erinaceum. Tetrahedron Lett. 1996; 37: 7399-7402
  23. The Anti-Dementia effect of Lion’s Mane mushroom and its clinical application – Hericium erinaceum – Lion’s Mane by Hirokazu Kawagishi Cun Zhuang Ellen Shnidman Townsend Letter for Doctors and Patients, April, 2004 by Hirokazu Kawagishi,Cun Zhuang, Ellen Shnidman
  24. Kolotushkina, E.V., M.G. Moldavan, K.Y. Voronin & G.G. Skibo, 2003. “The influence of Hericium erinaceus extract on myelination process in vitro.” Fiziologicheskii zhurnal 49(1): 38-45
  25. Kenmoku, H., T. Shimai, T. Toyomasu, N. Kato & T. Sassa, 2002. “Erinacine Q, a new erinacines from Hericium erinaceum, and its biosynthetic route to erinacines C in the basidiomycete.” Bioscience Biotechnology & Biochemistry Mar; 66(3)571-5
  26. K Mori, Y Obara, M Hirota, Y Azumi, S Kinugasa, S Inatomi, and N Nakahata Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells. Biol Pharm Bull, Sep 2008; 31(9): 1727-32
  27. K Mori, S Inatomi, K Ouchi, Y Azumi, and T Tuchida. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res, Mar 2009; 23(3): 367-72
  28. K Ueda, M Tsujimori, S Kodani, A Chiba, M Kubo, K Masuno, A Sekiya, K Nagai, and H Kawagishi An endoplasmic reticulum (ER) stress-suppressive compound and its analogues from the mushroom Hericium erinaceum. Bioorg Med Chem, November 1, 2008; 16(21): 9467-70
  29. K Ueda, M Tsujimori, S Kodani, A Chiba, M Kubo, K Masuno, A Sekiya, K Nagai, and H Kawagishi An endoplasmic reticulum (ER) stress-suppressive compound and its analogues from the mushroom Hericium erinaceum. Bioorg Med Chem, November 1, 2008; 16(21): 9467-70
  30. Moldavan MG, Grygansky AP, Kolotushkina OV, Kirchhoff B, Skibo GG, Pedarzani P. Neurotropic and Trophic Action of Lion’s Mane Mushroom Hericium erinaceus (Bull.: Fr.) Pers. (Aphyllophoromycetideae) Extracts on Nerve Cells in Vitro. IntJMedMushr. Year 2007,Vol. 9 (1): 15-28